This is key research because it says that everyone experiences a level of gut irritation and increased gut permeability from gluten.
Alessio Fasano, (read a very interesting interview with him here
) is internationally recognised for his work into celiac disease and gluten intolerance, was one of the researchers on this project.
In this video
he discusses why some people are unable to manage the immunologic reaction caused by the irritation, i.e. people with celiac disease and gluten sensitivity. And how the opened spaces in the gut wall remain open in these susceptible people causing severe problems.
The manifestation can be different for affected individuals depending upon genetic susceptibilities and weaknesses. For example, where one person may become depressed, another may become diabetic as a result of the inability to deal with ongoing gluten exposure.